Article
Demyelinating peripheral neuropathy in Creutzfeldt-Jakob disease.
Muscle & nerve - 1 Nov 1992
Neufeld M Y, Josiphov J, Korczyn A D
Abstract excerpt
We describe 2 patients of Jewish Libyan descent, who presented with a clinical syndrome compatible with Creutzfeldt-Jakob disease and who were found to have a mutation of codon 200 in the prion protein. The patients developed symptoms and signs of peripheral nerve involvement diagnosed by electrodiagnostic and histopathological studies as demyelinating neuropathy. This may be a rare manifestation of...
Topics
- Action Potentials
- Codon
- Creutzfeldt-Jakob Syndrome
- Demyelinating Diseases
- Electrodiagnosis
- Electromyography
- Humans
- Male
- Middle Aged
- Muscles
- Mutation
- Nerve Tissue Proteins