Article
Demyelinating peripheral neuropathy with Creutzfeldt-Jakob disease and mutation at codon 200 of the prion protein gene.
Neurology - 1 Apr 1996
Antoine J C, Laplanche J L, Mosnier J F, Beaudry P, Chatelain J, Michel D
Abstract excerpt
We performed a study of the distribution of PrP27-30, the proteinase-K-resistant form of prion protein, in the central and peripheral nervous system of a patient with a Glu200Lys mutation of the prion protein gene, cerebellar ataxia, subcortical dementia, rigidity, and demyelinating peripheral ne...
Topics
- Base Sequence
- Brain
- Codon
- Creutzfeldt-Jakob Syndrome
- Demyelinating Diseases
- Female
- Genes
- Humans
- Microscopy, Electron
- Middle Aged
- Molecular Biology
- Molecular Probes
- Molecular Sequence Data
- Mutation
- Peripheral Nerves
- Peripheral Nervous System Diseases