Improved predictive test for MEN2, using flanking dinucleotide repeats and RFLPs.

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Article

Improved predictive test for MEN2, using flanking dinucleotide repeats and RFLPs.

American journal of human genetics - 1 Dec 1992

Howe J R, Lairmore T C, Mishra S K, Dou S, Veile R, Wells S A, Donis-Keller H

Abstract excerpt

Gene(s) for the autosomal dominant endocrine cancer syndromes, multiple endocrine neoplasia type 2A (MEN2A), multiple endocrine neoplasia type 2B (MEN2B), and familial medullary thyroid carcinoma (MTC1) all map to the pericentromeric region of chromosome 10. Predictive testing for the inheritance of mutant alleles in individuals at risk for these disorders has been limited by the availability of highly...

Topics

Base Sequence
Chromosomes, Fungal
Chromosomes, Human, Pair 10
DNA, Single-Stranded
Female
Genetic Linkage
Genetic Markers
Genome, Human
Genomic Library
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

In Situ Hybridization, Fluorescence

Karyotyping

Male

Molecular Sequence Data

Multiple Endocrine Neoplasia

Pedigree

Polymorphism, Restriction Fragment Length

Source

Open in PubMed Open full text

Identifiers

PMID: 1361102
PMCID: PMC1682920

Genes

RBP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1361102-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Improved predictive test for MEN2, using flanking dinucleotide repeats and RFLPs.PMID 1361102Read ↗

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