Apparently non-expressed alleles of factor B (BF) code for hypomorphic proteins.

doi:10.1007/BF00223541

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Article

Apparently non-expressed alleles of factor B (BF) code for hypomorphic proteins.

Immunogenetics - 1 Jan 1992

Siemens I, Brenden M, Mauff G, Abbal M, Du Toit E, Bertrams J, Geserick G

Abstract excerpt

In three families with an apparent non-expressed factor B (BF) allele (BF*Q0), advanced methods of isoelectric focusing for the determination of BF F subtypes revealed different hypomorphic BF products (BF QL) with functional hemolytic activity expressed by the assumed BF*Q0 allele. A Taq I and a...

Topics

Alleles
Complement Factor B
Electrophoresis, Polyacrylamide Gel
Haplotypes
Hemolysis
Humans
Isoelectric Focusing
Polymorphism, Restriction Fragment Length

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