Article
Genomic analysis of the F subtypes of human complement factor B.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Dec 1994
Jahn I, Mejía J E, Thomas M, Darke C, Schröder H, Geserick G, Hauptmann G
Abstract excerpt
Factor B of human complement is encoded within the Major Histocompatibility Complex (MHC) and is polymorphic, with up to 30 alleles defined by electrophoretic mobility. One of the most common alleles, BF*F, is subdivided into the FA and FB subtypes, which differ at the gene level by non-synonymous base substitutions in the seventh codon. We have found at this position a new restriction site polymorphism, as a Bsl...
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