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Article

Analysis of the prion protein gene in thalamic dementia.

Neurology - 1 Oct 1992

Petersen R B, Tabaton M, Berg L, Schrank B, Torack R M, Leal S, Julien J, Vital C, Deleplanque B, Pendlebury W W

Abstract excerpt

Thalamic degenerations or dementias are poorly understood conditions. The familial forms are (1) selective thalamic degenerations and (2) thalamic degenerations associated with multiple system atrophy. Selective thalamic degenerations share clinical and pathologic features with fatal familial insomnia, an autosomal dominant disease linked to a mutation at codon 178 of the prion protein (PrP) gene that causes the...

Topics

Base Sequence
Dementia
Genes
Humans
Molecular Probes
Molecular Sequence Data
Mutation
Nerve Degeneration
Nerve Tissue Proteins
Pedigree
PrPSc Proteins
Prion Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prions

Thalamic Diseases

Source

Open in PubMed Open full text

Identifiers

PMID: 1357593
DOI: 10.1212/wnl.42.10.1859
PMCID: PMC6141000

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1357593-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Analysis of the prion protein gene in thalamic dementia.PMID 1357593Read ↗

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