Article
Natural scrapie in British sheep: breeds, ages and PrP gene polymorphisms.
The Veterinary record - 2 May 1992
Hunter N, Foster J D, Hope J
Abstract excerpt
One hundred and sixty-seven sheep of 32 breeds and crossbreeds affected by natural scrapie throughout Britain were tested for the presence of restriction fragment length polymorphisms of the PrP gene observed when their DNA was digested with EcoRI or HindIII. These polymorphisms have already been associated with different susceptibilities to experimental scrapie (controlled by alleles of the Sip gene) in a flock...
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