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Article

Associations between lamb survival and prion protein genotype: analysis of data for ten sheep breeds in Great Britain.

BMC veterinary research - 21 Jan 2009

Gubbins Simon, Cook Charlotte J, Hyder Kieran, Boulton Kay, Davis Carol, Thomas Eurion, Haresign Will, Bishop Stephen C, Villanueva Beatriz, Eglin Rachel D

Abstract excerpt

BACKGROUND: Selective breeding programmes, based on prion protein (PrP) genotype, have been introduced throughout the European Union to reduce the risk of sheep transmissible spongiform encephalopathies (TSEs). These programmes could have negative consequences on other important traits, such as fitness and production traits, if the PrP gene has pleiotropic effects or is in linkage disequilibrium with genes...

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Identifiers

PMID: 19159456
DOI: 10.1186/1746-6148-5-3
PMCID: PMC2637852

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