Article
Deletions, duplications and novel restriction fragment length polymorphism in Duchenne and Becker muscular dystrophies.
Clinical genetics - 1 May 1992
Lau Y L, Srivastava G, Wong V, Liu Y T, Ho F C, Yeung C Y
Abstract excerpt
To determine the mutations of Southern Chinese with Duchenne and Becker muscular dystrophies (DMD, BMD), we analysed 28 DMD and BMD patients in 24 unrelated families for intragenic deletions and duplications by using cDNA probes covering the entire 14 kb of the dystrophin gene. Deletions were det...
Topics
- Asian People
- Blotting, Southern
- Chromosome Deletion
- Densitometry
- Genetic Linkage
- Humans
- Multigene Family
- Muscular Dystrophies
- Mutation
- Polymorphism, Restriction Fragment Length