Article
Screening of deletions and RFLP analysis in Turkish DMD/BMD families by PCR.
Clinical genetics - 1 May 1993
Gökgöz N, Kuseyri F, Topaloğlu H, Yüksel-Apak M, Kirdar B
Abstract excerpt
We have screened 76 DMD and 5 BMD patients for deletions, using two separate Multiplex gene amplification systems. The use of both systems together revealed deletions in 52% of the cases in the Turkish population. The majority of these deletions (33/37) were found to be localized within the central region of the dystrophin gene. The remaining deletions were mapped to the proximal hotspot. Deletion end-points were...
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