Article
DNA analysis in Turkish Duchenne/Becker muscular dystrophy families.
Human genetics - 1 Aug 1992
Battaloğlu E, Telatar M, Deymeer F, Serdaroğlu P, Kuseyri F, Ozdemir C, Apak M, Tolun A
Abstract excerpt
The molecular genetics of Duchenne/Becker muscular dystrophy was investigated in 81 affected Turkish families. Deletions were detected by multiplex polymerase chain reaction assays and cDNA Southern analyses. The distribution of the deletions along the gene and their correlation to clinical phenotype were different from the studies reported on other populations. Moreover, DNA polymorphisms in mothers were...
Topics
- Chromosome Deletion
- DNA Mutational Analysis
- Humans
- Male
- Muscular Dystrophies
- Phenotype
- Polymorphism, Restriction Fragment Length
- Turkey