Article
Genetic and blood coagulation characterization of "Swedish" families with von Willebrand's disease types I and III: new aspects of heredity.
Human genetics - 1 May 1992
Anvret M, Blombäck M, Lindstedt M, Söderlind E, Tapper-Persson M, Thelander A C
Abstract excerpt
Twenty-five patients with von Willebrand's disease (vWD) type III were analysed with regard to blood coagulation variables and possible deletions. Nine of the probands and their families were further investigated with DNA linkage analyses. Different patterns of heredity can be suggested in our families with vWD type III, on the basis of blood coagulation analyses. The findings suggest homozygosity in five...
Topics
- Blood Coagulation
- Chromosome Deletion
- Enzyme-Linked Immunosorbent Assay
- Female
- Genetic Linkage
- Genetic Variation
- Humans
- Male
- Pedigree
- Polymorphism, Restriction Fragment Length
- Sweden