Article
Lymphocytotoxic strains of feline leukemia virus induce apoptosis in feline T4-thymic lymphoma cells.
Laboratory investigation; a journal of technical methods and pathology - 1 Apr 1992
Rojko J L, Fulton R M, Rezanka L J, Williams L L, Copelan E, Cheney C M, Reichel G S, Neil J C, Mathes L E, Fisher T G
Abstract excerpt
Feline leukemia retrovirus (FeLV) strains with subgroup C env genes kill feline T4 lymphoma 3201 cells by 7 to 12 days after in vitro inoculation, whereas FeLV strains with subgroup A env genes do not. Neither FeLV-A nor FeLV-C kill feline fibroblasts. FeLV-C, but not FeLV-A, is replicated to hig...
Topics
- Animals
- CD4-Positive T-Lymphocytes
- Cats
- Cell Cycle
- Cell Death
- DNA Damage
- Fibroblasts
- Genes, env
- Genetic Variation
- Leukemia Virus, Feline
- Leukemia, Feline
- Lipid Metabolism
- Lymphoma
- Neoplasms, Experimental
- Thymus Gland