Article
Barriers to Infection of Human Cells by Feline Leukemia Virus: Insights into Resistance to Zoonosis.
Journal of virology - 1 Mar 2017
Terry Anne, Kilbey Anna, Naseer Asif, Levy Laura S, Ahmad Shamim, Watts Ciorsdaidh, Mackay Nancy, Cameron Ewan, Wilson Sam, Neil James C
Abstract excerpt
The human genome displays a rich fossil record of past gammaretrovirus infections, yet no current epidemic is evident, despite environmental exposure to viruses that infect human cells in vitro Feline leukemia viruses (FeLVs) rank high on this list, but neither domestic nor workplace exposure has been associated with detectable serological responses. Nonspecific inactivation of gammaretroviruses by serum factors...
Topics
- APOBEC-3G Deaminase
- Animals
- Cats
- Cell Line, Tumor
- Disease Susceptibility
- Gene Expression
- Genome, Viral
- HEK293 Cells
- Humans
- Leukemia Virus, Feline
- Mutation
- Retroviridae Infections
- Species Specificity