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Article

Extensive allelic variation in Cryptococcus neoformans.

Journal of clinical microbiology - 1 May 1992

Casadevall A, Freundlich L F, Marsh L, Scharff M D

Abstract excerpt

The orotidine monophosphate pyrophosphorylase (OMPPase) gene locus of the DNA of 13 Cryptococcus neoformans var. neoformans strains, including 10 recent clinical isolates, was studied by using restriction fragment length polymorphisms and nucleotide sequence analysis. The OMPPase locus (URA5) is highly polymorphic, and at least six alleles were identified. The nucleotide sequences of some alleles differed by up...

Topics

Alleles
Base Sequence
Cryptococcus neoformans
Genes, Fungal
Genetic Variation
Molecular Sequence Data
Orotate Phosphoribosyltransferase
Polymorphism, Restriction Fragment Length

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1349897
DOI: 10.1128/jcm.30.5.1080-1084.1992
PMCID: PMC265228

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1349897-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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