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The internal transcribed spacers and 5.8S rRNA gene show extensive diversity among isolates of the Cryptococcus neoformans species complex.

FEMS yeast research - 1 Jan 2004

Katsu Masakazu, Kidd Sarah, Ando Akikazu, Moretti-Branchini Maria Luiza, Mikami Yuzuru, Nishimura Kazuko, Meyer Wieland

Abstract excerpt

Sequences of the internal transcribed spacer (ITS) region including the 5.8S rRNA gene delineated seven genotypes within the three varieties of Cryptococcus neoformans via specific combinations of eight nucleotide differences located at positions 10, 11, 15, 19, 108 (ITS1), 221 (5.8S), 298 and 346 (ITS2). The ITS types correlated to polymerase chain reaction fingerprint/random amplification of polymorphic DNA...

Topics

Base Sequence
Cryptococcus neoformans
Genetic Variation
Geography
Humans
Molecular Sequence Data
Phylogeny
Polymerase Chain Reaction
RNA, Fungal
RNA, Ribosomal, 18S

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription, Genetic

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Identifiers

PMID: 14734018
DOI: 10.1016/S1567-1356(03)00176-4

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