Article
Direct comparison of biological effectiveness of protons and alpha-particles of the same LET. II. Mutation induction at the HPRT locus in V79 cells.
International journal of radiation biology - 1 May 1992
Belli M, Goodhead D T, Ianzini F, Simone G, Tabocchini M A
Abstract excerpt
Mutation induction at the hprt locus has been studied in V79-4 Chinese hamster cells irradiated with mono-energetic protons and alpha-particles with LET of 20.3 and 23 keV microns-1. The mutation frequency increased linearly with the dose for all the four radiation qualities investigated, so that effectiveness for mutation induction could be expressed by the slope of the relevant curve. This effectiveness did not...
Topics
- Alpha Particles
- Animals
- Cell Line
- Energy Transfer
- Hypoxanthine Phosphoribosyltransferase
- Mutation
- Protons
- Radiation Genetics
- Relative Biological Effectiveness
