Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chromosome instability of HPRT-mutant subclones induced by ionising radiation of various LET.

Advances in space research : the official journal of the Committee on Space Research (COSPAR) - 1 Jan 2002

Govorun R D, Koshlan I V, Koshlan N A, Krasavin E A, Shmakova N L

Abstract excerpt

The induction of HPRT-mutations and survival of Chinese hamster cells (line B11ii-FAF28, clone 431) were studied after irradiation by 4He and 12C-ions of various LET (20-360 keV/micrometers), produced by the U-200 heavy ion accelerator. The RBE increases with LET up to the maximum at 100-200 keV/micrometers and then decreases. Cytogenetic analysis was performed on the HPRT-mutant subclones selected from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carbon
Share to Cell Physiological Phenomena

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosome Aberrations

Share to Cricetulus

Share to Dose-Response Relationship, Radiation

Share to Heavy Ions

Share to Hypoxanthine Phosphoribosyltransferase

Share to Linear Energy Transfer

Source

Identifiers

PMID: 12539752
DOI: 10.1016/s0273-1177(02)00407-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chromosome instability of HPRT-mutant subclones induced by ionising radiation of various LET.PMID 12539752Read ↗

Mutation induction by different types of radiation at the Hprt locus.Semantic proximity Read ↗

Delayed effects of accelerated heavy ions on the induction of HPRT mutations in V79 hamster cells.Semantic proximity Read ↗

Cellular and molecular analysis of mutagenesis induced by charged particles of defined linear energy transfer.Semantic proximity Read ↗

Multiplex polymerase chain reaction-based deletion analysis of spontaneous, gamma ray- and alpha-induced hprt mutants of CHO-K1 cells.Semantic proximity Read ↗

Induction of HPRT- mutants in Chinese hamster V79 cells after heavy ion exposure.Semantic proximity Read ↗

Dose-dependent changes in the spectrum of mutations induced by ionizing radiation.Semantic proximity Read ↗

Delayed appearance of radiation-induced mutations at the Hprt locus in murine hemopoietic cells.Semantic proximity Read ↗

Diverse delayed effects in human lymphoblastoid cells surviving exposure to high-LET (56)Fe particles or low-LET (137)Cs gamma radiation.Semantic proximity Read ↗

Molecular characterization of hprt mutants induced by low- and high-LET radiations in human cells.Semantic proximity Read ↗

Radiation induced chromosomal instability in human T-lymphocytes.Semantic proximity Read ↗

[Mutation induction by heavy ion beams and X-rays: analysis with cultured cell line].Semantic proximity Read ↗

HPRT mutations in V79 Chinese hamster cells induced by accelerated Ni, Au and Pb ions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.