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Article

Cell killing and mutation induction by heavy ion beams.

International journal of molecular medicine - 1 May 2001

Shigematsu N, Ihara N, Kawata T, Kawaguchi O, Takeda A, Ishibashi R, Kutsuki S, Kubo A, Kanai T, Furusawa Y, Isobe K, Uno T, Ito H

Abstract excerpt

Carbon beam radiotherapy for cancer patients was initiated in Japan in June 1994. This study attempts to clarify the radiobiological effects of heavy ion beams. In this study, human cancer cell lines (RMG-1, MDA-MB231) and V79 cells were used. The cell killing was determined by colony forming assay, and mutation induction was determined by counting the number of 6-thioguanine resistant colonies (hprt locus...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11295113
DOI: 10.3892/ijmm.7.5.509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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