Electrostatic interactions stabilizing ferredoxin electron transfer complexes. Disruption by "conservative" mutations.

Article

Electrostatic interactions stabilizing ferredoxin electron transfer complexes. Disruption by "conservative" mutations.

The Journal of biological chemistry - 5 May 1992

Coghlan V M, Vickery L E

Abstract excerpt

Mitochondrial ferredoxins mediate electron transfer from NADPH:ferredoxin oxidoreductase to cytochrome P450 enzymes. Previous studies on human ferredoxin, in which acidic residues were replaced with neutral amino acids, established that Asp-76 and Asp-79 are are important for binding to both redu...

Topics

Amino Acid Sequence
Aspartic Acid
Circular Dichroism
Electrochemistry
Electrons
Ferredoxins
Glutamates
Glutamic Acid
Humans
Molecular Sequence Data
Mutation
NADH Dehydrogenase
Spectrophotometry, Ultraviolet

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