Article
Electrostatic interactions stabilizing ferredoxin electron transfer complexes. Disruption by "conservative" mutations.
The Journal of biological chemistry - 5 May 1992
Coghlan V M, Vickery L E
Abstract excerpt
Mitochondrial ferredoxins mediate electron transfer from NADPH:ferredoxin oxidoreductase to cytochrome P450 enzymes. Previous studies on human ferredoxin, in which acidic residues were replaced with neutral amino acids, established that Asp-76 and Asp-79 are are important for binding to both reductase and P450 (Coghlan, V. M., and Vickery, L. E. (1991) J. Biol. Chem. 266, 18606-18612). Here we report that...
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