Article
Major histocompatibility complex located complement C4 and steroid 21-hydroxylase gene rearrangements in couples with recurrent spontaneous abortions.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Dec 1992
Laitinen T, Lokki M L, Partanen J, Tulppala M, Ylikorkala O, Koskimies S
Abstract excerpt
Major Histocompatibility Complex (MHC) class III located complement C4 and steroid 21-hydroxylase (21OH) genes, which form various deletion and duplication units, were studied by TaqI Restriction Fragment Length Polymorphism (RFLP) in 58 Finnish couples who suffered recurrent spontaneous abortions (RSA). The gene rearrangements found in the RSA couples did not differ from those in the controls.
Topics
- Abortion, Habitual
- Complement C4
- Female
- Gene Deletion
- Gene Rearrangement
- Humans
- Major Histocompatibility Complex
- Male
- Multigene Family
- Mutation