Hemoglobin Sabine [beta 91 (F7) Leu-->Pro]: occurrence in a Sardinian individual with hemolytic anemia and inclusion bodies.

Article

Hemoglobin Sabine [beta 91 (F7) Leu-->Pro]: occurrence in a Sardinian individual with hemolytic anemia and inclusion bodies.

Haematologica - 1 Jan 2000

Gasperini D, Galanello R, Melis M A, Iannelli S, Giordano P, Bernini L F, Cao A

Abstract excerpt

BACKGROUND: Hemoglobin (Hb) Sabine (beta 91 Leu-->Pro) is an unstable variant detected for the first time in a 16-year-old Scottish-English-German girl affected by moderately severe hemolytic anemia. A second case was described in a patient of Yugoslavian descent. We report another case of this H...

Topics

Adult
Anemia, Hemolytic
DNA Mutational Analysis
Erythrocytes
Globins
Hemoglobinopathies
Hemoglobins, Abnormal
Humans
Inclusion Bodies
Italy
Male
Mutation
Splenectomy

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.