Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation.

Nucleic acids research - 25 Oct 1992

Adachi N, Miyaike M, Ikeda H, Kikuchi A

Abstract excerpt

Several cDNA clones encoding mouse DNA topoisomerase II were obtained from a mouse spermatocyte cDNA library and the entire coding sequence of the gene was determined. The mouse DNA topoisomerase II consists of 1528 amino acids with a molecular weight of 173 kDa. It shares significant homologies with the other eucaryotic enzymes, although species-specific sequences are observed in their highly charged C-terminal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Molecular Sequence Data

Share to Mutation

Share to Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 1331984
DOI: 10.1093/nar/20.20.5297
PMCID: PMC334334

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation.PMID 1331984Read ↗

Mutant isolation of mouse DNA topoisomerase II alpha in yeast.Semantic proximity Read ↗

Mutations in topoisomerase IIβ result in a B cell immunodeficiencySemantic proximity Read ↗

Characterization of cDNA encoding mouse homolog of fission yeast dhp1+ gene: structural and functional conservation.Semantic proximity Read ↗

Cloning and characterization of mouse Dhm2 cDNA, a functional homolog of budding yeast SEP1.Semantic proximity Read ↗

Complementation of a yeast top2ts mutation by a cDNA encoding rat DNA topoisomerase II alpha.Semantic proximity Read ↗

Increased negative supercoiling of mtDNA in TOP1mt knockout mice and presence of topoisomerases II and II in vertebrate mitochondriaSemantic proximity Read ↗

Molecular characterization of a nuclear topoisomerase II from Nicotiana tabacum that functionally complements a temperature-sensitive topoisomerase II yeast mutant.Semantic proximity Read ↗

New Role for an Old Protein: An Educational Primer for Use with "The Identification of a Novel Mutant Allele of topoisomerase II in Caenorhabditis elegans Reveals a Unique Role in Chromosome Segregation During Spermatogenesis".Semantic proximity Read ↗

Infertility and aneuploidy in mice lacking a type IA DNA topoisomerase III beta.Semantic proximity Read ↗

Topoisomerase II is regulated by translationally controlled tumor protein for cell survival during organ growth in Drosophila.Semantic proximity Read ↗

Analysis of expression and function of topoisomerase I and II during meiosis in male miceSemantic proximity Read ↗

Cloning and characterization of DNA topoisomerase I gene Top1 from maize (Zea mays L.)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.