Article
Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation.
Nucleic acids research - 25 Oct 1992
Adachi N, Miyaike M, Ikeda H, Kikuchi A
Abstract excerpt
Several cDNA clones encoding mouse DNA topoisomerase II were obtained from a mouse spermatocyte cDNA library and the entire coding sequence of the gene was determined. The mouse DNA topoisomerase II consists of 1528 amino acids with a molecular weight of 173 kDa. It shares significant homologies...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- DNA Probes
- DNA Topoisomerases, Type II
- Escherichia coli
- Gene Library
- Genetic Complementation Test
- Mice
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Recombinant Proteins
- Yeasts