Article
A circadian clock of Drosophila: effects of deuterium oxide and mutations at the period locus.
Chronobiology international - 1 Aug 1992
White L, Ringo J, Dowse H
Abstract excerpt
Mutations at the period (per) locus (1:1.3; 3B1-2) in Drosophila melanogaster lengthen (perL), shorten (pers), or abolish (per0) overt circadian rhythmicity. Deuterium oxide lengthens the free-running circadian period. We tested the effects of deuterium on three mutants of the per gene (pers, perL, and per0) and wild-type Drosophila melanogaster (per+) to assess interactions. With increasing concentrations of...
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