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Article

Two major types of JC virus defined in progressive multifocal leukoencephalopathy brain by early and late coding region DNA sequences.

The Journal of general virology - 1 Oct 1992

Ault G S, Stoner G L

Abstract excerpt

A 610-bp region of the JC virus (JCV) genome sequenced from brains of 11 progressive multifocal leukoencephalopathy (PML) patients contains 20 sites of point mutations that allow reliable classification of JCV isolates into two types. These type-determining sites were located in the region extending from position 2131 in the VP1 gene, through the intergenic region, to position 2740 in the T antigen gene. At these...

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Source

Identifiers

PMID: 1328479
DOI: 10.1099/0022-1317-73-10-2669

Genes

PML

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