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Detection of Varicella-Zoster Virus DNA in Human Geniculate Ganglia by Polymerase Chain Reaction

1 Nov 1992

Abstract excerpt

Latent varicella-zoster virus (VZV) has been demonstrated in the human trigeminal and thoracic ganglia by means of nucleic acid hybridization. However, the human geniculate ganglia in VZV latency have not been examined. Tissue DNA extracted from the trigeminal and geniculate ganglia of a newborn and 7 adults was examined by polymerase chain reaction with a pair of VZV-specific primers. None had symptoms of recent...

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PMID: 1328403
DOI: 10.1093/infdis/166.5.1157

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