Article
Evolution of the primate lentiviruses: evidence from vpx and vpr.
The EMBO journal - 1 Sept 1992
Tristem M, Marshall C, Karpas A, Hill F
Abstract excerpt
The genomes of the four primate lentiviral groups are complex and contain several regulatory or accessory genes. Two of these genes, vpr and vpx, are found in various combinations within the four groups and encode proteins whose functions have yet to be elucidated. Comparison of the encoded protein sequences suggests that the vpx gene within the HIV-2 group arose by the duplication of an ancestral vpr gene within...
Topics
- Amino Acid Sequence
- Animals
- Biological Evolution
- Gene Products, vpr
- Genes, Viral
- Genetic Variation
- HIV-2
- Lentivirus
- Molecular Sequence Data
- Multigene Family
- Phylogeny
- Primates