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Article

Retinoic acid and its rearranged receptor in the etiology and treatment of acute promyelocytic leukemia.

Oncology (Williston Park, N.Y.) - 1 Aug 1992

Frankel S R, Miller W H, Dmitrovsky E

Abstract excerpt

All-trans retinoic acid can induce complete remissions in patients with acute promyelocytic leukemia. The balanced chromosomal translocation t(15;17)(q22;q12-21) of this malignancy is now known to involve the nuclear retinoic acid receptor-alpha (RAR-alpha) on the long arm of chromosome 17 and a novel gene on the long arm of chromosome 15, designated PML (previously called myl). A unique fusion mRNA,...

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Identifiers

PMID: 1323988

Genes

PML

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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