Article
Lymphocyte subsets associated with T cell receptor beta-chain gene rearrangement in patients with rheumatoid arthritis and neutropenia.
Arthritis and rheumatism - 1 May 1992
Gonzales-Chambers R, Przepiorka D, Winkelstein A, Agarwal A, Starz T W, Kline W E, Hawk H
Abstract excerpt
OBJECTIVE: To determine the incidence of a clonal lymphoid disease in patients with chronic rheumatoid arthritis (RA) and neutropenia. METHODS: Lymphocytes from 23 RA patients with either current neutropenia or a history of this complication were studied. RESULTS: Eight patients had a clonal rearrangement of the T cell receptor beta-chain gene. Phenotypically, they showed a distinctive pattern characterized by an...
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