Article
Hereditary flat adenoma syndrome: a variant of familial adenomatous polyposis?
Diseases of the colon and rectum - 1 May 1992
Lynch H T, Smyrk T C, Watson P, Lanspa S J, Lynch P M, Jenkins J X, Rouse J, Cavalieri J, Howard L, Lynch J
Abstract excerpt
We describe the clinical and pathologic features in four extended kindreds that are consistent with the hereditary flat adenoma syndrome (HFAS). This colon cancer susceptibility disorder is believed to be inherited as an autosomal dominant. The principal phenotypic marker is multiple colonic adenomas (usually less than 100), with a tendency for proximal location. The majority of these adenomas are flat or...
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