Article
Colonic adenoma risk in familial colorectal cancer--a study of six extended kindreds.
The American journal of gastroenterology - 1 Oct 2008
Neklason Deborah W, Thorpe Brett L, Ferrandez Angel, Tumbapura Anil, Boucher Kenneth, Garibotti Gilda, Kerber Richard A, Solomon Cindy H, Samowitz Wade S, Fang John C, Mineau Geraldine P, Leppert Mark F, Burt Randall W, Kuwada Scott K
Abstract excerpt
OBJECTIVES: Most colorectal cancers (CRCs) arise from adenomatous polyps, but the effects of CRC family history on adenoma risk are not well known. This issue is clinically relevant since several medical societies currently recommend earlier and more rigorous colorectal screening for individuals with a strong family history of CRC. METHODS: Colonoscopies were performed in 236 first-, second-, and third-degree...
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