Attenuated familial adenomatous polyposis (AFAP). A review of the literature.

doi:10.1023/a:1023286520725

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Article

Attenuated familial adenomatous polyposis (AFAP). A review of the literature.

Familial cancer - 1 Jan 2003

Knudsen Anne Lyster, Bisgaard Marie Luise, Bülow Steffen

Abstract excerpt

Over the last decade, a subset of familial adenomatous polyposis (FAP) patients with a milder course of disease termed attenuated familial adenomatous polyposis (AFAP) has been described. AFAP is not well-defined as a disease entity - the reports on AFAP are largely casuistic or only deal with a few kindreds--and the diagnostic criteria and methods of investigation differ markedly. The true incidence and...

Topics

Adenoma
Adenomatous Polyposis Coli
Adult
Aged
Colectomy
Colorectal Neoplasms
Female
Genotype
Humans
Incidence
Male
Middle Aged
Mutation
Phenotype
Prognosis
Time Factors

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Open in PubMed

Identifiers

PMID: 14574166
DOI: 10.1023/a:1023286520725

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