Inhibitory effect of oryzacystatins and a truncation mutant on the replication of poliovirus in infected Vero cells.

doi:10.1016/0014-5793(92)80097-z

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Article

Inhibitory effect of oryzacystatins and a truncation mutant on the replication of poliovirus in infected Vero cells.

FEBS letters - 24 Mar 1992

Kondo H, Ijiri S, Abe K, Maeda H, Arai S

Abstract excerpt

Poliovirus, a picornavirus family member, requires the processing of its poly-protein by its own cysteine proteinase for replication. Oryzacystatin-I and oryzacystatin-II, proteinaceous cysteine proteinase inhibitors (cystatins) of rice seed origin, were found to inhibit the replication of poliov...

Topics

Animals
Cystatins
Cysteine Proteinase Inhibitors
Mutation
Poliovirus
Vero Cells
Virus Replication

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