Article
The use of cysteine proteinase inhibitors to engineer resistance against potyviruses in transgenic tobacco plants.
Nature biotechnology - 1 Dec 1999
Gutierrez-Campos R, Torres-Acosta J A, Saucedo-Arias L J, Gomez-Lim M A
Abstract excerpt
As the processing mechanism of all known potyviruses involves the activity of cysteine proteinases, we asked whether constitutive expression of a rice cysteine proteinase inhibitor gene could induce resistance against two important potyviruses, tobacco etch virus (TEV) and potato virus Y (PVY), in transgenic tobacco plants. Tobacco lines expressing the foreign gene at varying levels were examined for resistance...
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