Article
[Analysis of oncogenes and suppressor genes in lung cancer and bronchial lesions from high risk group].
Nihon Kyobu Shikkan Gakkai zasshi - 1 Dec 1992
Awaya Y, Hiyama K, Yamakido M
Abstract excerpt
The authors investigated methods for analysis of oncogenes and tumor suppressor genes in lung cancers and bronchial lesions from high risk patients (retired poison gas factory workers). Amplifications of C-, L-, N-myc, length of terminal repeat array (TRA), mutations of p53 gene, p53 mRNA and K-ras genes were analysed in frozen specimens of surgically resected lung cancers. Various lesions including dysplasia,...
Topics
- Bronchi
- Gases
- Gene Amplification
- Genes, myc
- Genes, p53
- Genes, ras
- Humans
- Hyperplasia
- Lung Neoplasms
- Metaplasia
- Mutation
- Occupational Exposure