Article
Retinoic acid receptor and retinoid X receptor alterations in lung cancer precursor lesions.
Cancer research - 1 Jun 2000
Martinet N, Alla F, Farré G, Labib T, Drouot H, Vidili R, Picard E, Gaube M P, Le Faou D, Siat J, Borelly J, Vermylen P, Bazarbachi T, Vignaud J M, Martinet Y
Abstract excerpt
Smoking prevention will decrease lung cancer incidence in time. However, early detection would improve lung cancer prognosis in subjects at risk provided that specific markers could be identified. We previously reported that retinoic acid receptor (RAR) and retinoid X receptor (RXR) expression was altered in lung tumors. RAR-beta gene status could be derived from corresponding allelotyping and...
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