Article
Variability of the expression of muscle mitochondrial damage in ocular mitochondrial myopathy.
Neuromuscular disorders : NMD - 1 Jan 1992
Siciliano G, Rossi B, Angelini C, Martinuzzi A, Carrozzo R, Bevilacqua G, Viacava P, Federico A, Fabrizi G M, Muratorio A
Abstract excerpt
In this study we comparatively analysed deltoid histochemistry, biochemistry and mitochondrial DNA (mtDNA) in two groups of ten sporadic ocular mitochondrial myopathies (OMM), respectively with and without ragged red fibres (RRF). (1) All but one RRF--patients presented the mild form of OMM with blepharoptosis but without ophthalmoplegia; (2) the occurrence of cytochrome c oxidase deficient (COX-) fibres was...
Topics
- Adolescent
- Adult
- Aged
- Blepharoptosis
- Child
- DNA, Mitochondrial
- Female
- Humans
- Male
- Middle Aged
- Mitochondria, Muscle
- Mitochondrial Myopathies