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Article

Contribution of muscle biopsy and genetics to the diagnosis of chronic progressive external opthalmoplegia of mitochondrial origin.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Apr 2011

Sundaram Challa, Meena A K, Uppin Megha S, Govindaraj P, Vanniarajan A, Thangaraj K, Kaul Subhash, Kekunnaya Ramesh, Murthy J M K

Abstract excerpt

Chronic progressive external opthalmoplegia (CPEO) is the most common phenotypic syndrome of the mitochondrial myopathies. Muscle biopsy, which provides important morphological clues for the diagnosis of mitochondrial disorders, is normal in approximately 25% of patients with CPEO, thus necessitating molecular genetic analysis for more accurate diagnosis. We aimed to study the utility of various histochemical...

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Identifiers

PMID: 21277779
DOI: 10.1016/j.jocn.2010.06.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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