Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single muscle fiber analysis of myoclonus epilepsy with ragged-red fibers.

Muscle & nerve - 1 Apr 1998

Mita S, Tokunaga M, Uyama E, Kumamoto T, Uekawa K, Uchino M

Abstract excerpt

We examined two muscle biopsy specimens from a proband and her mother with myoclonus epilepsy with ragged-red fibers (MERRF), both obtained at an interval of about 10 years, using histochemistry, in situ hybridization, and single-fiber polymerase chain reaction. Total (wild-type and mutant) mitochondrial DNAs (mtDNAs) were greatly increased in ragged-red fibers (RRF) over non-RRF in all muscle specimens analyzed....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Mitochondrial
Share to Histocytochemistry
Share to In Situ Hybridization

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to MERRF Syndrome

Share to Mitochondria, Muscle

Share to Muscle, Skeletal

Share to Mutation

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 9533783
DOI: 10.1002/(sici)1097-4598(199804)21:4<490::aid-mus7>3.0.co;2-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single muscle fiber analysis of myoclonus epilepsy with ragged-red fibers.PMID 9533783Read ↗

Molecular Diagnosis of Myoclonus Epilepsy Associated with Ragged-Red Fibers Syndrome in the Absence of Ragged Red FibersSemantic proximity Read ↗

When should MERRF (myoclonus epilepsy associated with ragged-red fibers) be the diagnosis?Semantic proximity Read ↗

A common mitochondrial DNA mutation in the t-RNA(Lys) of patients with myoclonus epilepsy associated with ragged-red fibers.Semantic proximity Read ↗

[Myoclonus epilepsy with ragged-red fibers: a case report and literature review].Semantic proximity Read ↗

Identification of new variants in MTRNR1 and MTRNR2 genes using whole mitochondrial genome sequencing in a Taiwanese family with MERRF (myoclonic epilepsy with ragged-red fibers) syndrome.Semantic proximity Read ↗

Late-onset Leigh syndrome with myoclonic epilepsy with ragged-red fibers.Semantic proximity Read ↗

A double mutation (A8296G and G8363A) in the mitochondrial DNA tRNA <sup>Lys</sup> gene associated with myoclonus epilepsy with ragged-red fibersSemantic proximity Read ↗

A molecular genetic study of focal histochemical defects in mitochondrial encephalomyopathies.Semantic proximity Read ↗

Genetic heterogeneity of myoclonus epilepsy with ragged-red fibers syndrome.Semantic proximity Read ↗

Myoclonus epilepsy and ragged-red fibers: blood mitochondrial DNA heteroplasmy in affected and asymptomatic members of a family.Semantic proximity Read ↗

Tissue segregation of a heteroplasmic mtDNA mutation in MERRF (myoclonic epilepsy with ragged red fibers) encephalomyopathy.Semantic proximity Read ↗

A new mitochondrial transfer RNAPro gene mutation associated with myoclonic epilepsy with ragged-red fibers and other neurological features.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.