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Type II gonadotrophin-releasing hormone (GnRH-II) in reproductive biology

1 Sept 2003

Abstract excerpt

Humans may be particularly unusual with respect to the gonadotrophin-releasing hormone (GnRH) control of their reproductive axis in that they possess two distinct GnRH precursor genes, on chromosomes 8p11-p21 and 20p13, but only one conventional GnRH receptor subtype (type I GnRH receptor) encoded within the genome, on chromosome 4. A disrupted human type II GnRH receptor gene homologue is present on chromosome...

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PMID: 12968935
DOI: 10.1530/rep.0.1260271

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