Article
Retention and silencing of prepro-GnRH-II and type II GnRH receptor genes in mammals.
Neuroendocrinology - 1 Jan 2009
Stewart Alan J, Katz Arieh A, Millar Robert P, Morgan Kevin
Abstract excerpt
The decapeptide hypothalamic-pituitary gonadotrophin-releasing hormone (GnRH)-I and the type I GnRH receptor drive the reproductive hormonal cascade in mammals by stimulating synthesis and secretion of luteinising hormone (LH) and follicle stimulating hormone (FSH). Mammals possess a second GnRH system composed of a related hormone, GnRH-II (differing from GnRH-I by three amino acid residues), and the type II...
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