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Article

Retention and silencing of prepro-GnRH-II and type II GnRH receptor genes in mammals.

Neuroendocrinology - 1 Jan 2009

Stewart Alan J, Katz Arieh A, Millar Robert P, Morgan Kevin

Abstract excerpt

The decapeptide hypothalamic-pituitary gonadotrophin-releasing hormone (GnRH)-I and the type I GnRH receptor drive the reproductive hormonal cascade in mammals by stimulating synthesis and secretion of luteinising hormone (LH) and follicle stimulating hormone (FSH). Mammals possess a second GnRH system composed of a related hormone, GnRH-II (differing from GnRH-I by three amino acid residues), and the type II...

Topics

Amino Acid Sequence
Animals
Genome
Gonadotropin-Releasing Hormone
Humans
Mammals
Molecular Sequence Data
Mutation
Protein Precursors
Receptors, LHRH
Sequence Alignment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, DNA

Sequence Homology, Amino Acid

Species Specificity

Source

Identifiers

PMID: 19657181
DOI: 10.1159/000233303

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