Article
Cdx-2 polymorphism in the promoter region of the human vitamin D receptor gene determines susceptibility to fracture in the elderly.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Sept 2003
Fang Yue, van Meurs Joyce B J, Bergink Arjan P, Hofman Albert, van Duijn Cornelia M, van Leeuwen Johannes P T M, Pols Huibert A P, Uitterlinden André G
Abstract excerpt
UNLABELLED: A Cdx-2 binding site polymorphism (G to A) in the promoter region of the human vitamin D receptor gene was reported. In an ecological study in eight ethnic groups and an association study in 2848 elderly whites, we found the A-allele to be associated with decreased fracture risk. Our...
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