Article
HSP70-2 (HSPA1B) is associated with noncognitive symptoms in late-onset Alzheimer's disease.
Journal of geriatric psychiatry and neurology - 1 Sept 2003
Clarimón Jordi, Bertranpetit Jaume, Boada Mercè, Tàrraga Lluís, Comas David
Abstract excerpt
Neuropsychiatric manifestations are common in Alzheimer's disease (AD) and their phenotypic expression might be related to physiopathological and genetic causes. Multiple studies have implicated oxidative stress to the pathogenesis and possible etiology of AD. One of the mechanisms to protect cells from oxidative stress is the expression of heat-shock proteins (HSP). HSPA1B (alternatively known as HSP70-2) has...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
