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Article

Identification of Naf1/ABIN‐1 among TNF‐α‐induced expressed genes in human synoviocytes using oligonucleotide microarrays

9 Aug 2003

Abstract excerpt

The cytokine tumor necrosis factor alpha (TNF-alpha) is a critical effector of the pathogenesis of rheumatoid arthritis (RA). We used oligonucleotide microarray (OM) analysis to assess TNF-alpha-modulated gene expression in cultured primary human synoviocytes in vitro. Genes identified include cytokines and inflammatory mediators, extracellular matrix and adhesion molecules, cell cycle and proliferation related...

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PMID: 12965196
DOI: 10.1016/s0014-5793(03)00823-8

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