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Analysis of Secreted Proteins for the Study of Bladder Cancer Cell Aggressiveness

28 Apr 2010

Abstract excerpt

Secreted proteins play a key role in cell signaling, communication, and migration. We recently described the development of an aggressive variant (T24M) of the bladder cancer cell line T24. Using this cell line model, the objective of our work was the identification of secreted proteins involved in the acquisition of the aggressive phenotype. Using in vitro assays, we demonstrate that conditioned media of the...

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PMID: 20423150
DOI: 10.1021/pr100189d

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