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Article

Omeprazole disposition in children following single-dose administration.

Journal of clinical pharmacology - 1 Aug 2003

Kearns Gregory L, Andersson Tommy, James Laura P, Gaedigk Andrea, Kraynak Rebecca A, Abdel-Rahman Susan M, Ramabadran Krishnaswami, van den Anker John N

Abstract excerpt

UNLABELLED: Omeprazole is frequently used to treat gastroesophageal reflux in infants and children despite the lack of age-specific pharmacokinetic and dosing information in the approved product labeling. To address this challenge, the authors examined the potential influence of development and cytochrome P450 2C19 (CYP2C19) genotype on omeprazole disposition by conducting two pharmacokinetic (PK) studies in...

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Source

Identifiers

PMID: 12953341
DOI: 10.1177/0091270003256122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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