Article
Metabolism of omeprazole after two oral doses in children 1 to 9 months old.
Proceedings of the Western Pharmacology Society - 1 Jan 2005
Hoyo-Vadillo Carlos, Venturelli Caterina R, González Hector, Romero Elba, Cervantes Roberto, Mata Norberto, Ortiz Ana Carolina, Rincón Victor, Zarate Flora, Sosa Cristina, Ramírez-Mayans Jaime
Abstract excerpt
Proton pump inhibitors (PPIs) have been used recently for gastrointestinal esophageal reflux disease (GERD) in children older than one year with good results. However, the pharmacokinetics of PPIs have not been studied in children less than two years old. The aim of our study was to evaluate the frequency of the main phenotypes of the metabolizing enzymes CYP2C19 and CYP3A4 in Mexican infants. Our results...
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