Article
Molecular targeting with recombinant cytotoxins of interleukin-13 receptor alpha2-expressing glioma.
Journal of neuro-oncology - 1 Jan 2000
Mintz Akiva, Gibo Denise M, Madhankumar A B, Debinski Waldemar
Abstract excerpt
A restricted receptor for interleukin 13 (IL-13R alpha2) is over-expressed in high-grade astrocytoma (HGA), but not in normal organs. In order to design and examine new anti-HGA therapies, which are molecularly directed against IL-13R alpha2, we established an IL-13R alpha2-expressing syngeneic i...
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