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Article

A review of the advances in understanding the genetic basis of spondylarthritis and emerging clinical benefit.

Best practice & research. Clinical rheumatology - 1 Dec 2024

Stadler Michael, Zhao Sizheng Steven, Bowes John

Abstract excerpt

Spondyloarthropathies (SpA), including ankylosing spondylitis (AS) and psoriatic arthritis (PsA), have been shown to have a substantial genetic predisposition based on heritability estimates derived from family studies and genome-wide association studies (GWAS). GWAS have uncovered numerous genetic loci associated with susceptibility to SpA, with significant associations to human leukocyte antigen (HLA) genes,...

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Source

Identifiers

PMID: 39223061
DOI: 10.1016/j.berh.2024.101982

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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