Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Ala45Thr polymorphism of BETA2/NeuroD1 gene and susceptibility to type 1 diabetes mellitus in caucasians.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Aug 2003

Malecki M T, Klupa T, Moczulski D K, Rogus J J

Abstract excerpt

It has recently been shown that mutations in BETA2/NeuroD1 are responsible for the development of type 2 diabetes mellitus (T2DM) in Caucasians. This gene is located near the IDDM7 region and one of its amino acid polymorphisms, Ala45Thr, has been associated with type 1 diabetes (T1DM) in Japanese and Danish populations. The aim of our study is to examine Ala45Thr for its role in T1DM in Caucasians. We used both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Alanine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Basic Helix-Loop-Helix Transcription Factors

Share to Diabetes Mellitus, Type 1

Share to Reference Values

Share to Threonine

Share to Trans-Activators

Share to White People

Source

Identifiers

PMID: 12951629
DOI: 10.1055/s-2003-41282

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Ala45Thr polymorphism of BETA2/NeuroD1 gene and susceptibility to type 1 diabetes mellitus in caucasians.PMID 12951629Read ↗

Evaluation of variant A45T in NEUROD1/BETA2 for its association with type 2 diabetes mellitus.Semantic proximity Read ↗

Ala45Thr polymorphism of the NEUROD1 gene and diabetes susceptibility: a meta-analysis.Semantic proximity Read ↗

Lack of association of the Ala45Thr variant in the BETA2/NEUROD1 with type 1 diabetes in Japanese.Semantic proximity Read ↗

The Ala45Thr polymorphism of NEUROD1 is associated with type 1 diabetes in Brazilian women.Semantic proximity Read ↗

The Ala45Thr polymorphism of BETA2/NeuroD1 gene and susceptibility to type 2 diabetes mellitus in a Polish population.Semantic proximity Read ↗

Association of polymorphism in the NeuroD/BETA2 gene with type 1 diabetes in the Japanese.Semantic proximity Read ↗

Neuronal Differentiation 1 gene Ala45Thr polymorphism and type 2 diabetes mellitus: A meta-analysis of 7,940 subjects.Semantic proximity Read ↗

The association of Ala45Thr polymorphism in NeuroD with child-onset Type 1a diabetes in Japanese.Semantic proximity Read ↗

NeuroD/BETA2 gene variability and diabetes: no associations to late-onset type 2 diabetes but an A45 allele may represent a susceptibility marker for type 1 diabetes among Danes. Danish Study Group of Diabetes in Childhood, and the Danish IDDM Epidemiology and Genetics Group.Semantic proximity Read ↗

Ala45Thr variation in neuroD1 gene is associated with early-onset type 2 diabetes with or without diabetic pedigree in Chinese.Semantic proximity Read ↗

Lack of association of the Ala(45)Thr polymorphism and other common variants of the NeuroD gene with type 1 diabetes.Semantic proximity Read ↗

Association between type 2 diabetes and CDKN2A/B: a meta-analysis study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.